Dr. Margaret Sleeper 2011 Books and Publications

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Book: Feline Cardiology http://www.wiley.com/WileyCDA/WileyTitle/productCd-0813812429.html

It is for the vet field, primarily students, techs or vets who work with cats. , and we are quite proud of it.

I have 11 scientific publications for 2011 (listed below) and I am still searching for funds to begin a canine clinical trial using gene therapy to treat heart disease.

1.Long-term Restoration of Cardiac Dystrophin Expression in Golden Retriever Muscular Dystrophy Following rAAV6-mediated Exon Skipping.

Bish LT, Sleeper MM, Forbes SC, Wang B, Reynolds C, Singletary GE, Trafny D, Morine KJ, Sanmiguel J, Cecchini S, Virag T, Vulin A, Beley C, Bogan J, Wilson JM, Vandenborne K, Kornegay JN, Walter GA, Kotin RM, Garcia L, Sweeney HL.

Mol Ther. 2011 Dec 6. doi: 10.1038/mt.2011.264. [Epub ahead of print]

PMID: 22146342 [PubMed – as supplied by publisher]Related citations

2.Use of an implantable loop recorder in the investigation of arrhythmias in adult captive chimpanzees (Pan troglodytes).

Lammey ML, Jackson R, Ely JJ, Lee DR, Sleeper MM.

Comp Med. 2011 Feb;61(1):71-5.

PMID: 21819684 [PubMed – in process] Free PMC Article

Related citations

3.Long-Term Systemic Myostatin Inhibition via Liver-Targeted Gene Transfer in Golden Retriever Muscular Dystrophy.

Bish LT, Sleeper MM, Forbes SC, Morine KJ, Reynolds C, Singletary GE, Trafny D, Pham J, Bogan J, Kornegay JN, Vandenborne K, Walter GA, Sweeney HL.

Hum Gene Ther. 2011 Dec;22(12):1499-509. Epub 2011 Aug 30.

PMID: 21787232 [PubMed – in process]Related citations

4.Cardiac magnetic resonance in the differentiation of neoplastic and nonneoplastic pericardial effusion.

Boddy KN, Sleeper MM, Sammarco CD, Weisse C, Ghods S, Litt HI.

J Vet Intern Med. 2011 Sep;25(5):1003-9. doi: 10.1111/j.1939-1676.2011.0762.x. Epub 2011 Jul 22.

PMID: 21781165 [PubMed – in process]Related citations

5.Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice.

Bish LT, Yarchoan M, Sleeper MM, Gazzara JA, Morine KJ, Acosta P, Barton ER, Sweeney HL.

PLoS One. 2011;6(6):e20856. Epub 2011 Jun 22.

PMID: 21731628 [PubMed – indexed for MEDLINE] Related citations

6.Effects of aging and blood contamination on the urinary protein-creatinine ratio in captive chimpanzees (Pan troglodytes).

Lammey ML, Ely JJ, Zavaskis T, Videan E, Sleeper MM.

J Am Assoc Lab Anim Sci. 2011 May;50(3):374-7.

PMID: 21640034 [PubMed – indexed for MEDLINE] Free PMC Article

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7.Transendocardial delivery of AAV6 results in highly efficient and global cardiac gene transfer in rhesus macaques.

Gao G, Bish LT, Sleeper MM, Mu X, Sun L, Lou Y, Duan J, Hu C, Wang L, Sweeney HL.

Hum Gene Ther. 2011 Aug;22(8):979-84. Epub 2011 Jun 24.

PMID: 21563985 [PubMed – in process]

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8.Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines.

Bish LT, Sleeper MM, Reynolds C, Gazzara J, Withnall E, Singletary GE, Buchlis G, Hui D, High KA, Gao G, Wilson JM, Sweeney HL.

Hum Gene Ther. 2011 Aug;22(8):969-77. Epub 2011 Jun 8.

PMID: 21542669 [PubMed – in process]

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9.Association of brain-type natriuretic protein and cardiac troponin I with incipient cardiovascular disease in chimpanzees (Pan troglodytes).

Ely JJ, Zavaskis T, Lammey ML, Sleeper MM, Lee DR.

Comp Med. 2011 Apr;61(2):163-9.

PMID: 21535928 [PubMed – indexed for MEDLINE] Free PMC Article

Related citations

10.Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 in the canine.

Bish LT, Sleeper MM, Sweeney HL.

Methods Mol Biol. 2011;709:369-78.

PMID: 21194041 [PubMed – indexed for MEDLINE]

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11.Long-term amelioration of feline Mucopolysaccharidosis VI after AAV-mediated liver gene transfer.

Cotugno G, Annunziata P, Tessitore A, O’Malley T, Capalbo A, Faella A, Bartolomeo R, O’Donnell P, Wang P, Russo F, Sleeper MM, Knox VW, Fernandez S, Levanduski L, Hopwood J, De Leonibus E, Haskins M, Auricchio A.

Mol Ther. 2011 Mar;19(3):461-9. Epub 2010 Nov 30.

PMID: 21119624 [PubMed – indexed for MEDLINE]

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